This paper details the development of an integrated AC electro-osmotic (ACEO) microfluidic pump for dilute electrolytes consisting of a long serpentine microchannel lined with three dimensional (3D) stepped electrode arrays. Using low AC voltage (1 V rms, 1 kHz), power (5 mW) and current (4.5 mA) in water, the pump is capable of generating a 1.3 kPa head pressure, a 100-fold increase over prior ACEO pumps, and a 1.3 mm/s effective slip velocity over the electrodes without flow reversal. The integrated ACEO pump can utilize low ionic strength solutions such as distilled water as the working solution to pump physiological strength (100 mM) biological solutions in separate microfluidic devices, with potential applications in portable or implantable biomedical microfluidic devices. As a proof-of-concept experiment, the use of the ACEO pumps for DNA hybridization in a microfluidic microarray is demonstrated.
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机译：本文详细介绍了用于稀薄电解质的集成交流电渗透（ACEO）微流体泵的开发过程，该泵由长的蜿蜒微通道组成，衬有三维（3D）阶梯式电极阵列。在水中使用低交流电压（1 V rms，1 kHz），功率（5 mW）和电流（4.5 mA）时，该泵能够产生1.3 kPa的扬程压力，比以前的ACEO泵高100倍，并且电极上的有效滑动速度为1.3 mm / s，无逆流现象。集成的ACEO泵可以利用低离子强度溶液（例如蒸馏水）作为工作溶液，以在单独的微流体设备中泵送生理强度（100 mM）的生物溶液，在便携式或可植入生物医学微流体设备中具有潜在的应用。作为概念验证实验，证明了使用ACEO泵在微流控微阵列中进行DNA杂交。
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